Despite its vast power, the sinister Umbrella Corporation has begun to lose control of its hidden research facilities. Three labs have already been destroyed by rogue S.T.A.R.S., former members of the paramilitary response unit Umbrella helped create.

Beneath the deserts of the American Southwest, one of the Umbrella Corporation's most elaborate facilities is about to go online. Somewhere inside may also be the key to stopping Umbrella once and for all... if Leon S. Kennedy, Claire Redfield, Rebecca Chambers, and their friends can get past a strike team of corrupt S.T.A.R.S., and survive the genetically engineered horrors awaiting them below the sun-scorched earth.

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